Article
Ubiquitin-independent entry into the yeast recycling pathway.
Traffic (Copenhagen, Denmark) - 1 Feb 2002
Chen Linyi, Davis Nicholas G
Abstract excerpt
The yeast a-factor receptor (Ste3p) is subject to two mechanistically distinct modes of endocytosis: a constitutive, ligand-independent pathway links to vacuolar degradation of the receptor, while a ligand-dependent uptake pathway links primarily to recycling and thus, receptor reutilization. Ste3p ubiquitination triggers its uptake into the constitutive pathway. The present work considers the role of the...
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