Article
HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis.
Gut - 1 Sept 1999
Stokkers P C, Reitsma P H, Tytgat G N, van Deventer S J
Abstract excerpt
BACKGROUND: Susceptibility to inflammatory bowel disease (IBD) is partially genetically determined and the HLA class II genes are candidates for a role in genetic susceptibility to IBD, because their products play a central role in the immune response. Multiple studies have reported associations between HLA-DR or -DQ phenotypes and either ulcerative colitis or Crohn's disease, but much of the data are still...
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