Article
A defect in nurturing in mice lacking the immediate early gene fosB.
Cell - 26 Jul 1996
Brown J R, Ye H, Bronson R T, Dikkes P, Greenberg M E
Abstract excerpt
Although expression of the Fos family of transcription factors is induced by environmental stimuli that trigger adaptive neuronal response, evidence that Fos family members mediate these responses is lacking. To address this issue, mice were generated with an inactivating mutation in the fosB gene. fosB mutant mice are profoundly deficient in their ability to nurture young animals but are normal with respect to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.