Article
Cyclic AMP response element-binding protein is required for normal maternal nurturing behavior.
Neuroscience - 1 Jan 2005
Jin S-H, Blendy J A, Thomas S A
Abstract excerpt
Analysis of mice with targeted disruptions of fosB or the gene encoding dopamine beta-hydroxylase suggests that FosB and adrenergic signaling play critical roles in maternal nurturing behavior. The majority of neonates born to null females from either mutation fail to thrive, and virgin mutant females of both lines exhibit impaired pup retrieval. Considering whether FosB and adrenergic signaling might share a...
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