Article
Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.
The EMBO journal - 1 Sept 1990
Lucibello F C, Slater E P, Jooss K U, Beato M, Müller R
Abstract excerpt
In this study, we show that Fos protein can repress transactivation by the glucocorticoid receptor (GR). In addition, we demonstrate that GR is capable of inhibiting, in a hormone-dependent fashion, Fos-mediated transactivation of AP-1 dependent transcription. Moreover, repression of the serum re...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA-Binding Proteins
- Enzyme Repression
- HeLa Cells
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes