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Article

Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.

The EMBO journal - 1 Sept 1990

Lucibello F C, Slater E P, Jooss K U, Beato M, Müller R

Abstract excerpt

In this study, we show that Fos protein can repress transactivation by the glucocorticoid receptor (GR). In addition, we demonstrate that GR is capable of inhibiting, in a hormone-dependent fashion, Fos-mediated transactivation of AP-1 dependent transcription. Moreover, repression of the serum response element by Fos is abolished by the GR in the presence of hormone. Transrepression of glucocorticoid mediated...

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Identifiers

PMID: 2118106
DOI: 10.1002/j.1460-2075.1990.tb07471.x
PMCID: PMC551994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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