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Article

Hippocampal expression of c-fos is not essential for spatial learning.

Synapse (New York, N.Y.) - 1 Nov 2002

Zhang Jianhua, McQuade Jill M Slane, Vorhees Charles V, Xu Ming

Abstract excerpt

The formation of long-term memory is thought to involve underlying changes in synaptic strength. Many studies have focused on the mechanisms of spatial learning behavior in mammals that is critically dependent on the proper function of the hippocampus. Because of the enduring nature of long-term memory, it is thought that gene expression is involved in this process. The immediate early gene (IEG) c-fos encodes a...

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PMID: 12211087
DOI: 10.1002/syn.10115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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