Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>Fos</i> B mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine’s psychomotor and rewarding effects

16 Sept 1997

Abstract excerpt

Chronic exposure to cocaine leads to prominent, long-lasting changes in behavior that characterize a state of addiction. The striatum, including the nucleus accumbens and caudoputamen, is an important substrate for these actions. We previously have shown that long-lasting Fos-related proteins of 35-37 kDa are induced in the striatum by chronic cocaine administration. In the present study, the identity and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurotransmitter Receptor Influence on Behavior
Share to Parkinson's Disease Mechanisms and Treatments
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9294222
DOI: 10.1073/pnas.94.19.10397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>Fos</i> B mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine’s psychomotor and rewarding effectsPMID 9294222Read ↗

Functional role of the N-terminal domain of ΔFosB in response to stress and drugs of abuse.Semantic proximity Read ↗

Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine.Semantic proximity Read ↗

Opiate sensitization induces FosB/ΔFosB expression in prefrontal cortical, striatal and amygdala brain regions.Semantic proximity Read ↗

c-Fos is an intracellular regulator of cocaine-induced long-term changes.Semantic proximity Read ↗

CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum.Semantic proximity Read ↗

Serum Response Factor Promotes Resilience to Chronic Social Stress through the Induction of ΔFosBSemantic proximity Read ↗

Reduced cue-induced reinstatement of cocaine-seeking behavior in Plcb1+/- miceSemantic proximity Read ↗

Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments.Semantic proximity Read ↗

Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal.Semantic proximity Read ↗

Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action.Semantic proximity Read ↗

Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stressSemantic proximity Read ↗

Cell-Type-Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.