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Article

Structural topology of transmembrane helix 10 in the lactose permease of Escherichia coli.

The Journal of biological chemistry - 6 Sept 1996

Goswitz V C, Matzke E A, Taylor M R, Jessen-Marshall A E, Brooker R J

Abstract excerpt

In the lactose permease of Escherichia coli, transmembrane helix 10 has been shown to be functionally important. The structure of this helix has been examined in greater detail in this study. A total of 46 substitution and 8 insertional mutants were constructed and analyzed along the entire length of transmembrane helix 10. The results identified amino acids that are tolerant of substitutions by a variety of...

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Identifiers

PMID: 8702996
DOI: 10.1074/jbc.271.36.21927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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