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Article

Identification of a glycine motif required for packing in EmrE, a multidrug transporter from Escherichia coli.

The Journal of biological chemistry - 2 May 2008

Elbaz Yael, Salomon Tal, Schuldiner Shimon

Abstract excerpt

Glycine residues may play functional and structural roles in membrane proteins. In this work we studied the role of glycine residues in EmrE, a small multidrug transporter from Escherichia coli. EmrE extrudes various drugs across the plasma membrane in exchange with protons and, as a result, confers resistance against their toxic effects. Each of 12 glycine residues was replaced by site-directed mutagenesis. Four...

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Identifiers

PMID: 18321856
DOI: 10.1074/jbc.M710338200
PMCID: PMC2431008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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