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Article

Helix packing in the lactose permease of Escherichia coli: localization of helix VI.

Journal of molecular biology - 7 Sept 2001

Guan L, Weinglass A B, Kaback H R

Abstract excerpt

Plasmids encoding "split" lactose permease constructs with discontinuities in either the periplasmic loop between helices V and VI (N(5)/C(7)) or between helices VI and VII (N(6)/C(6)) were used to localize helix VI within the tertiary structure by site-directed thiol cross-linking. A total of 57 double-Cys pairs, with one Cys residue in helix VI and another in helix V or VIII, were studied with homobifunctional...

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Identifiers

PMID: 11545586
DOI: 10.1006/jmbi.2001.4933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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