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Article

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling.

Nature - 8 Aug 1996

van den Heuvel M, Ingham P W

Abstract excerpt

Members of the Hedgehog family of secreted proteins control a number of important inductive interactions in the development of both vertebrates and Drosophila, but little is known about the ways in which their signalling activities are transduced. In Drosophila, hedgehog is one of the segment-pol...

Topics

Alleles
Amino Acid Sequence
Animals
Chromosome Mapping
Drosophila
Drosophila Proteins
Female
Hedgehog Proteins
Male
Membrane Proteins
Molecular Sequence Data
Proteins
Proto-Oncogene Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Cell Surface

Receptors, G-Protein-Coupled

Signal Transduction

Smoothened Receptor

Wnt1 Protein

Source

Identifiers

PMID: 8700230
DOI: 10.1038/382547a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8700230-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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