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Article

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling.

Nature - 8 Aug 1996

van den Heuvel M, Ingham P W

Abstract excerpt

Members of the Hedgehog family of secreted proteins control a number of important inductive interactions in the development of both vertebrates and Drosophila, but little is known about the ways in which their signalling activities are transduced. In Drosophila, hedgehog is one of the segment-polarity genes, mutations of which disrupt the pattern and polarity of individual embryonic segments and their adult...

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Identifiers

PMID: 8700230
DOI: 10.1038/382547a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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smoothened encodes a receptor-like serpentine protein required for hedgehog signalling.PMID 8700230Read ↗

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Regulation of the oncoprotein Smoothened by small molecules.Semantic proximity Read ↗

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