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Article

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

Nature - 6 Dec 2001

Hong Y, Stronach B, Perrimon N, Jan L Y, Jan Y N

Abstract excerpt

Establishing cellular polarity is critical for tissue organization and function. Initially discovered in the landmark genetic screen for Drosophila developmental mutants, bazooka, crumbs, shotgun and stardust mutants exhibit severe disruption in apicobasal polarity in embryonic epithelia, resulting in multilayered epithelia, tissue disintegration, and defects in cuticle formation. Here we report that stardust...

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PMID: 11740559
DOI: 10.1038/414634a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.PMID 11740559Read ↗

crumbs and stardust, two genes of Drosophila required for the development of epithelial cell polarity.Semantic proximity Read ↗

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Antagonistic functions of two stardust isoforms in Drosophila photoreceptor cells.Semantic proximity Read ↗

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.Semantic proximity Read ↗

Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster.Semantic proximity Read ↗

Multiple domains of Stardust differentially mediate localisation of the Crumbs-Stardust complex during photoreceptor development in Drosophila.Semantic proximity Read ↗

Drosophila Lin-7 is a component of the Crumbs complex in epithelia and photoreceptor cells and prevents light-induced retinal degeneration.Semantic proximity Read ↗

Cell type-specific recruitment of Drosophila Lin-7 to distinct MAGUK-based protein complexes defines novel roles for Sdt and Dlg-S97.Semantic proximity Read ↗

glaikit is essential for the formation of epithelial polarity and neuronal development.Semantic proximity Read ↗

Dynein regulates epithelial polarity and the apical localization of stardust A mRNA.Semantic proximity Read ↗

Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust.Semantic proximity Read ↗

The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family.Semantic proximity Read ↗

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