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Article

Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling.

Development (Cambridge, England) - 1 Feb 2002

Micchelli Craig A, The Inge, Selva Erica, Mogila Vladic, Perrimon Norbert

Abstract excerpt

Members of the Hedgehog (Hh) family encode secreted molecules that act as potent organizers during vertebrate and invertebrate development. Post-translational modification regulates both the range and efficacy of Hh protein. One such modification is the acylation of the N-terminal cysteine of Hh. In a screen for zygotic lethal mutations associated with maternal effects, we have identified rasp, a novel Drosophila...

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Identifiers

PMID: 11861468
DOI: 10.1242/dev.129.4.843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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