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Article

Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies

1 Jul 1996

Abstract excerpt

We have previously described complement-independent killing of human B lymphocytes by two IgM MoAbs derived from the VH4-34 (VH4.21) gene. Analysis of 17 independently derived VH4-34-encoded MoAbs shows that B cell toxicity is not limited to the two described MoAbs, but is a general property shared by a subset of MoAbs derived from the VH4-34 gene. As observed by two independent microscopy techniques, giant...

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Identifiers

PMID: 8697629
DOI: 10.1046/j.1365-2249.1996.d01-733.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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