Article
Structural analysis of VH4-21 encoded human IgM allo- and autoantibodies against red blood cells.
Scandinavian journal of immunology - 1 Jul 1995
Børretzen M, Chapman C, Stevenson F K, Natvig J B, Thompson K M
Abstract excerpt
We have sequenced the variable heavy chain regions of a number of VH4-21 encoded monoclonal IgM anti-Rh(D) antibodies produced in response to deliberate immunization. These were compared with the sequences of similarly encoded IgM anti-I cold agglutinins (CA) derived from patients with lympho-pro...
Topics
- Agglutinins
- Amino Acid Sequence
- Antibodies, Monoclonal
- Autoantibodies
- Base Sequence
- Carbohydrates
- Cryoglobulins
- Erythrocytes
- Humans
- I Blood-Group System
- Immunoglobulin Heavy Chains
- Immunoglobulin M
- Immunoglobulin Variable Region
- Isoantibodies
- Molecular Sequence Data
- Mutation
- Rh-Hr Blood-Group System