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Article

Structural analysis of VH4-21 encoded human IgM allo- and autoantibodies against red blood cells.

Scandinavian journal of immunology - 1 Jul 1995

Børretzen M, Chapman C, Stevenson F K, Natvig J B, Thompson K M

Abstract excerpt

We have sequenced the variable heavy chain regions of a number of VH4-21 encoded monoclonal IgM anti-Rh(D) antibodies produced in response to deliberate immunization. These were compared with the sequences of similarly encoded IgM anti-I cold agglutinins (CA) derived from patients with lympho-proliferative diseases. The anti-Rh(D) antibodies show evidence of clonal expansion and somatic diversification. Even...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7631150
DOI: 10.1111/j.1365-3083.1995.tb03630.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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