Abundance and state of phosphorylation of the retinoblastoma gene product in human pituitary tumors.

doi:10.1002/(SICI)1097-0215(19960703)67:1<16::AID-IJC4>3.0.CO;2-2

Back to search

Article

Abundance and state of phosphorylation of the retinoblastoma gene product in human pituitary tumors.

International journal of cancer - 3 Jul 1996

Woloschak M, Yu A, Xiao J, Post K D

Abstract excerpt

Targeted disruptions of the retinoblastoma (Rb) gene result in a high frequency of pituitary tumors in heterozygous mice. While our group and others have reported that loss of heterozygosity (LOH) at the Rb locus in human pituitary tumors is rare, these studies have not excluded small inactivatin...

Topics

Base Sequence
DNA, Neoplasm
Female
Humans
Male
Molecular Sequence Data
Mutation
Phosphorylation
Pituitary Neoplasms
Polymorphism, Single-Stranded Conformational
Retinoblastoma Protein

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.