Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic susceptibility to leishmanial infections: studies in mice and man.

Parasitology - 1 Jan 1996

Blackwell J M

Abstract excerpt

Two important recent advances in Leishmania immunology are: (i) the demonstration of a dramatic dichotomy in T helper 1 versus T helper 2 subset expansion leading to protection versus disease exacerbation; and (ii) analysis of the macrophage activation pathways leading to enhanced intracellular killing of parasites, in particular the tumour necrosis factor alpha (TNF alpha)-dependent sustained induction of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 6
Share to TNF gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Major Histocompatibility Complex

Source

Identifiers

PMID: 8684837

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic susceptibility to leishmanial infections: studies in mice and man.PMID 8684837Read ↗

Genetics of host resistance and susceptibility to intramacrophage pathogens: a study of multicase families of tuberculosis, leprosy and leishmaniasis in north-eastern Brazil.Semantic proximity Read ↗

Immunogenetics of leishmanial and mycobacterial infections: the Belem Family Study.Semantic proximity Read ↗

Genetic analysis of Leishmania mexicana infection in mice: single gene (Scl-2) controlled predisposition to cutaneous lesion development.Semantic proximity Read ↗

Genetics and visceral leishmaniasis: of mice and man.Semantic proximity Read ↗

Single gene effects in mouse models of host: pathogen interactions.Semantic proximity Read ↗

Susceptibility to mycobacterial infections: the importance of host genetics.Semantic proximity Read ↗

Genetic susceptibility to infectious disease: lessons from mouse models of leishmaniasis.Semantic proximity Read ↗

Genetics of susceptibility to leishmaniasis in mice: four novel loci and functional heterogeneity of gene effects.Semantic proximity Read ↗

Genetics of murine leishmaniasis.Semantic proximity Read ↗

Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites.Semantic proximity Read ↗

Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases.Semantic proximity Read ↗

Susceptibility and resistance in leprosy: Studies in the mouse modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.