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Article

Single gene effects in mouse models of host: pathogen interactions.

Journal of leukocyte biology - 1 Jun 2005

Fortier Anne, Min-Oo Gundula, Forbes John, Lam-Yuk-Tseung Steven, Gros Philippe

Abstract excerpt

Inbred mouse strains have been known for many years to vary in their degree of susceptibility to different types of infectious diseases. The genetic basis of these interstrain differences is sometimes simple but often complex. In a few cases, positional cloning has been used successfully to identify single gene effects. The natural resistance-associated macrophage protein 1 (Nramp1) gene (Slc11a1) codes for a...

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PMID: 15653750
DOI: 10.1189/jlb.1004616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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