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Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jun 1999

Fowell D J, Locksley R M

Abstract excerpt

Leishmania major infection of inbred mice leads to a major dichotomous response--death or survival--that depends on the strain of mice. This finding has motivated efforts to locate genetic determinants of disease susceptibility. Genotyping studies have confirmed a complex multilocus trait, but studies directed at the biology of the response suggest identifiable components of susceptibility that may direct the...

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Identifiers

PMID: 10402957
DOI: 10.1002/(SICI)1521-1878(199906)21:6<510::AID-BIES7>3.0.CO;2-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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