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Article

Immunogenetics of leishmanial and mycobacterial infections: the Belem Family Study.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Sept 1997

Blackwell J M, Black G F, Peacock C S, Miller E N, Sibthorpe D, Gnananandha D, Shaw J J, Silveira F, Lins-Lainson Z, Ramos F, Collins A, Shaw M A

Abstract excerpt

In the 1970s and 1980s, analysis of recombinant inbred, congenic and recombinant haplotype mouse strains permitted us to effectively 'scan' the murine genome for genes controlling resistance and susceptibility to leishmanial infections. Five major regions of the genome were implicated in the control of infections caused by different Leishmania species which, because they show conserved synteny with regions of the...

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PMID: 9355125
DOI: 10.1098/rstb.1997.0118
PMCID: PMC1692031

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