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Article

Position specificity of Ki-ras oncogene mutations during the progression of colorectal carcinoma.

Oncology - 1 Jan 1993

Rochlitz C F, Heide I, de Kant E, Böhmer R, Peter F J, Neuhaus P, Huhn D, Herrmann R

Abstract excerpt

The Ki-ras proto-oncogene is converted into an active oncogene by mutations in codon 12, 13, or 61. The incidence of mutations in the Ki-ras oncogene in colorectal adenomas and primary colorectal carcinomas has been shown to be 50-75 and 40-65%, respectively. To determine the role activation of the Ki-ras oncogene plays in the progression of colorectal carcinoma, we analyzed DNA from 11 nude-mouse xenografts and...

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Identifiers

PMID: 8421601
DOI: 10.1159/000227150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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