Article
p53 alterations in oesophageal cancer: association with clinicopathological features, risk factors, and survival.
Molecular pathology : MP - 1 Apr 1998
Casson A G, Tammemagi M, Eskandarian S, Redston M, McLaughlin J, Ozcelik H
Abstract excerpt
AIM: To characterise the spectrum of p53 alterations (gene mutations and protein accumulation) in a consecutive series of surgically resected oesophageal cancers, and to evaluate associations with clinicopathological findings (age, sex, tumour histology, grade, and stage), potential risk factors...
Topics
- Adult
- Aged
- Biomarkers, Tumor
- Esophageal Neoplasms
- Female
- Follow-Up Studies
- Genes, p53
- Humans
- Immunoenzyme Techniques
- Male
- Middle Aged
- Mutation
- Neoplasm Proteins
- Prognosis
- Prospective Studies
- Risk Factors
- Survival Rate
- Tumor Suppressor Protein p53