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Article

Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30.

Molecular biology of the cell - 1 May 2012

Carrillo Emilio, Ben-Ari Giora, Wildenhain Jan, Tyers Mike, Grammentz Dilon, Lee Traci A

Abstract excerpt

Yeast sulfur metabolism is transcriptionally regulated by the activator Met4. Met4 lacks DNA-binding ability and relies on interactions with Met31 and Met32, paralogous proteins that bind the same cis-regulatory element, to activate its targets. Although Met31 and Met32 are redundant for growth in the absence of methionine, studies indicate that Met32 has a prominent role over Met31 when Met30, a negative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22438580
DOI: 10.1091/mbc.E11-06-0532
PMCID: PMC3350556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30.PMID 22438580Read ↗

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