Article
Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.
Molecular and cellular biology - 1 Dec 1995
Thomas D, Kuras L, Barbey R, Cherest H, Blaiseau P L, Surdin-Kerjan Y
Abstract excerpt
A specific repression mechanism regulates the biosynthesis of sulfur amino acids in Saccharomyces cerevisiae. When the intracellular S-adenosylmethionine (AdoMet) concentration increases, transcription of the sulfur genes is repressed. Using a specific reporter system, we have isolated mutations...
Topics
- Amino Acid Sequence
- Base Sequence
- Carbon-Oxygen Lyases
- Cysteine Synthase
- F-Box Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genetic Complementation Test
- Genotype
- Lyases
- Molecular Sequence Data
- Multienzyme Complexes
- Oxidoreductases
- Repetitive Sequences, Nucleic Acid