Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.

Molecular and cellular biology - 1 Dec 1995

Thomas D, Kuras L, Barbey R, Cherest H, Blaiseau P L, Surdin-Kerjan Y

Abstract excerpt

A specific repression mechanism regulates the biosynthesis of sulfur amino acids in Saccharomyces cerevisiae. When the intracellular S-adenosylmethionine (AdoMet) concentration increases, transcription of the sulfur genes is repressed. Using a specific reporter system, we have isolated mutations impairing the AdoMet-mediated transcriptional regulation of the sulfur network. These mutations identified a new gene,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Genetic Complementation Test

Share to Genotype

Share to Molecular Sequence Data

Share to Restriction Mapping

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8524217
DOI: 10.1128/MCB.15.12.6526
PMCID: PMC230905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.PMID 8524217Read ↗

Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex.Semantic proximity Read ↗

Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30.Semantic proximity Read ↗

Identification of residues in the WD-40 repeat motif of the F-box protein Met30p required for interaction with its substrate Met4p.Semantic proximity Read ↗

A dominant suppressor mutation of the met30 cell cycle defect suggests regulation of the Saccharomyces cerevisiae Met4-Cbf1 transcription complex by Met32.Semantic proximity Read ↗

Single point mutations in Met4p impair the transcriptional repression of MET genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA.Semantic proximity Read ↗

Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast.Semantic proximity Read ↗

Profiling the compendium of changes in Saccharomyces cerevisiae due to mutations that alter availability of the main methyl donor S-Adenosylmethionine.Semantic proximity Read ↗

Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.Semantic proximity Read ↗

SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition.Semantic proximity Read ↗

A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae.Semantic proximity Read ↗

Comprehensive structural and substrate specificity classification of the Saccharomyces cerevisiae methyltransferome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.