p53 expression in four human medulloblastoma-derived cell lines.

doi:10.1007/BF00819500

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Article

p53 expression in four human medulloblastoma-derived cell lines.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Feb 1996

Srinivasan J, Berger M S, Silber J R

Abstract excerpt

p53 is a tumor suppressor gene found on the short arm of chromosome 17. Loss of one p53 allele and alteration of the other is found in a variety of tumors, including highgrade glial tumors. Point mutations in the remaining allele occur in a highly conserved region of the gene encompassing exons 5...

Topics

Alleles
Chromosomes, Human, Pair 17
DNA Damage
Gene Amplification
Gene Deletion
Gene Expression
Genes, p53
Heterozygote
Humans
Medulloblastoma
Point Mutation
Polymerase Chain Reaction
RNA, Messenger
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8674085
DOI: 10.1007/BF00819500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8674085-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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