Molecular changes involved in the carcinogenesis of brain tumors.

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Article

Molecular changes involved in the carcinogenesis of brain tumors.

Folia neuropathologica - 1 Jan 1994

Debiec-Rychter M, Liberski P P

Abstract excerpt

Current basic research on tumorigenesis suggests that the accumulation of multiple genetic defects underlies the progression of initiated cells toward malignancy. Molecular abnormalities associated with primary brain tumors include a wide variety of changes in tumor-suppressor genes, proto-oncoge...

Topics

Base Sequence
Biomarkers, Tumor
Brain Neoplasms
Chromosome Aberrations
Chromosome Disorders
ErbB Receptors
Gene Expression
Genes, Tumor Suppressor
Genes, p53
Humans
Molecular Sequence Data
Mutagenesis
Neuroglia
Phenotype
Proto-Oncogenes
RNA, Messenger
Transforming Growth Factor alpha

Source

Open in PubMed

Identifiers

PMID: 7889330

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7889330-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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