Article
Allelic imbalance on chromosome 17p13 in borderline (low malignant potential) epithelial ovarian tumors.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 1999
Zanotti K M, Hart W R, Kennedy A W, Belinson J L, Casey G
Abstract excerpt
Borderline epithelial ovarian tumors (BEOTs) possess clinical and pathologic features intermediate between cystadenomas and cystadenocarcinomas. Although the clinical and pathologic characteristics of BEOTs are well described, the molecular aspects are poorly understood. Three regions of loss of heterozygosity (often referred to as allelic imbalance [AI] when identified by polymerase chain reaction) on chromosome...
Topics
- Alleles
- Chromosomes, Human, Pair 17
- Cystadenocarcinoma, Mucinous
- Cystadenocarcinoma, Serous
- Female
- Genes, p53
- Humans
- Loss of Heterozygosity
- Ovarian Neoplasms
- Polymerase Chain Reaction
