Article
Role of a signal transduction pathway which controls disassembly of microfilament bundles and suppression of high-molecular-weight tropomyosin expression in oncogenic transformation of NRK cells.
Oncogene - 16 May 1996
Masuda A, Takenaga K, Kondoh F, Fukami H, Utsumi K, Okayama H
Abstract excerpt
Role of disassembly of microfilament bundles and suppression of high-molecular-weight tropomyosin (TM) expression in growth factor- and various oncogene-induced transformation was studied by using NRK cells and its transformation-deficient mutants. In NRK cells which show a transformed phenotype...
Topics
- Actin Cytoskeleton
- Actins
- Animals
- Cell Transformation, Neoplastic
- Epidermal Growth Factor
- Gene Expression
- Isomerism
- Mice
- Mutation
- Oncogenes
- Signal Transduction
- Tropomyosin