Article
Regulation of tropomyosin expression in transformed granulosa cell lines with steroidogenic ability.
Developmental biology - 1 Nov 1990
Baum G, Suh B S, Amsterdam A, Ben-Ze'ev A
Abstract excerpt
The expression of the different tropomyosin isoforms was analyzed in primary granulosa cell cultures and in established granulosa cell lines cotransfected with SV40 and Ha-ras DNA which retain a high steroidogenic response to cAMP stimulation. In contrast to normal cells which greatly reduce the expression of all tropomyosin isoforms during development of steroidogenic ability, in the doubly transformed cells...
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