Tropomyosin-2 cDNA lacking the 3' untranslated region riboregulator induces growth inhibition of v-Ki-ras-transformed fibroblasts.

doi:10.1091/mbc.8.5.897

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Article

Tropomyosin-2 cDNA lacking the 3' untranslated region riboregulator induces growth inhibition of v-Ki-ras-transformed fibroblasts.

Molecular biology of the cell - 1 May 1997

Janssen R A, Mier J W

Abstract excerpt

The levels of high molecular weight isoforms of tropomyosin (TM) are markedly reduced in ras-transformed cells. Previous studies have demonstrated that the forced expression of tropomyosin-1 (TM-1) induces reversion of the transformed phenotype of ras-transformed fibroblasts. The effects of the r...

Topics

3T3 Cells
Animals
Calcium-Calmodulin-Dependent Protein Kinases
Cell Division
Cell Line, Transformed
Cell Transformation, Neoplastic
DNA, Complementary
Gene Expression Regulation
Genes, ras
Introns
JNK Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mitogen-Activated Protein Kinase 1

Mitogen-Activated Protein Kinase 3

Mitogen-Activated Protein Kinases

Phenotype

Protein-Tyrosine Kinases

Tropomyosin

Source

Open in PubMed Open full text

Identifiers

PMID: 9168473
DOI: 10.1091/mbc.8.5.897
PMCID: PMC276136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9168473-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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