Article
T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant.
The Journal of experimental medicine - 1 Apr 1996
Kalams S A, Johnson R P, Dynan M J, Hartman K E, Harrer T, Harrer E, Trocha A K, Blattner W A, Buchbinder S P, Walker B D
Abstract excerpt
Numerous virus-specific, class I-restricted cytotoxic T lymphocyte (CTL) epitopes have been identified, yet little information is available regarding the specificity of the CTL response in persons of the same human histocompatibility leukocyte antigen (HLA) type. In this study, the human immunodeficiency virus (HIV) 1 envelope-specific CTL response was evaluated in five HLA-B14-positive persons. CTL responses...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.