Article
Fine-specificity of cytotoxic T lymphocytes which recognize conserved epitopes of the Gag protein of human immunodeficiency virus type 1.
The Journal of general virology - 1 Aug 1996
van Baalen C A, Klein M R, Huisman R C, Dings M E, Kerkhof Garde S R, Geretti A M, Gruters R, van Els C A, Miedema F, Osterhaus A D
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) Gag-specific cytotoxic T lymphocyte (CTL) responses were studied in seven seropositive long-term asymptomatic individuals (CDC A1) with stable CD4 counts for more than 8 years. Using a set of partially overlapping peptides covering the whole Gag, five 15-20-mer peptides were found to contain CTL epitopes. Further characterization of these epitopes revealed a new...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
