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Article

Detection of a mutator phenotype in cancer cells by inter-Alu polymerase chain reaction.

Cancer research - 15 Jun 1996

Krajinovic M, Richer C, Labuda D, Sinnett D

Abstract excerpt

A mutator phenotype due to a DNA mismatch repair deficiency is usually detected by typing a number of microsatellite markets. Here, eight hereditary nonpolyposis colon cancer patients with microsatellite instability were investigated by inter-Alu PCR, known to amplify DNA segments that may represent preferential targets of replication errors. Among 40-60 bands revealed in a single PCR experiment, more than 20%...

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PMID: 8665504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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