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Article

Telomere instability detected in sporadic colon cancers, some showing mutations in a mismatch repair gene.

Oncogene - 22 Apr 2004

Pickett Hilda Amelia, Baird Duncan Martin, Hoff-Olsen Per, Meling Gunn Iren, Rognum Torleiv Ole, Shaw Jacqui, West Kevin Paul, Royle Nicola Jane

Abstract excerpt

Human telomeres are essential for genome stability and are composed of long simple tandem repeat arrays (STRs), comprising the consensus TTAGGG repeat interspersed, at the proximal end, with sequence-variant repeats. While the dynamics of telomere attrition through incomplete replication has been...

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Share to Base Pair Mismatch
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Transforming Growth Factor beta

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Source

Identifiers

PMID: 15048084
DOI: 10.1038/sj.onc.1207477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15048084-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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