Article
Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae.
Science (New York, N.Y.) - 17 Dec 1993
Foss M, McNally F J, Laurenson P, Rine J
Abstract excerpt
In Saccharomyces cerevisiae, the HMR-E silencer blocks site-specific interactions between proteins and their recognition sequences in the vicinity of the silencer. Silencer function is correlated with the firing of an origin of replication at HMR-E. An essential gene with a role in transcriptiona...
Topics
- Alleles
- Amino Acid Sequence
- Cell Cycle
- Cloning, Molecular
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Origin Recognition Complex
- Phenotype
- Plasmids
- Replicon
- Repressor Proteins
- Saccharomyces cerevisiae