Article
Yeast origin recognition complex functions in transcription silencing and DNA replication.
Science (New York, N.Y.) - 17 Dec 1993
Bell S P, Kobayashi R, Stillman B
Abstract excerpt
The genes encoding two of the subunits of the Saccharomyces cerevisiae origin recognition complex (ORC) have been isolated. Characterization of a temperature-sensitive mutation in the gene encoding the 72-kD subunit of ORC (ORC2) indicates that this protein complex functions early in the DNA repl...
Topics
- Amino Acid Sequence
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Mating Type, Fungal
- Molecular Sequence Data
- Mutation
- Origin Recognition Complex
- Replicon
- Repressor Proteins
- S Phase
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Temperature
- Transcription, Genetic