Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytochrome P4502E1 genotypes, alcoholism, and alcoholic cirrhosis in Han Chinese and Atayal Natives of Taiwan.

Alcoholism, clinical and experimental research - 1 Feb 1996

Carr L G, Yi I S, Li T K, Yin S J

Abstract excerpt

Genetic factors may play a role in the development of alcoholic liver disease (ALD). Cytochrome P4502E1 (CYP2E1) catalyzes the oxidation of ethanol, producing acetaldehyde and free radicals capable of reacting with and peroxidizing cell membranes. Polymorphisms have been identified in the 5-flanking region of the CYP2E1 gene that may alter the transcriptional activity. In our laboratory, no difference in c1 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cytochrome P-450 Enzyme System
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Carrier Screening

Share to Genetics, Population

Share to Homozygote

Share to Risk Factors

Source

Identifiers

PMID: 8651460
DOI: 10.1111/j.1530-0277.1996.tb01041.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytochrome P4502E1 genotypes, alcoholism, and alcoholic cirrhosis in Han Chinese and Atayal Natives of Taiwan.PMID 8651460Read ↗

Polymorphism at the P450IIE1 locus is not associated with alcoholic liver disease in Caucasian men.Semantic proximity Read ↗

Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population.Semantic proximity Read ↗

An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population.Semantic proximity Read ↗

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men.Semantic proximity Read ↗

CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese.Semantic proximity Read ↗

Genetic polymorphisms of genes coding to alcohol-metabolizing enzymes in western Mexicans: association of CYP2E1*c2/CYP2E1*5B allele with cirrhosis and liver function.Semantic proximity Read ↗

Alcoholism and Alcoholic Organ Damage and Genetic Polymorphisms of Alcohol Metabolizing Enzymes in Chinese PatientsSemantic proximity Read ↗

Genetic polymorphism of cytochrome P4502E1 and risk of alcoholic liver disease in Caucasians.Semantic proximity Read ↗

ALDH2, ADH1B, and ADH1C genotypes in Asians: a literature review.Semantic proximity Read ↗

Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease.Semantic proximity Read ↗

No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population.Semantic proximity Read ↗

Genetic polymorphism of two enzymes with alcoholic liver disease in Northeast China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.