Article
An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population.
Hepatology (Baltimore, Md.) - 1 Nov 1995
Chao Y C, Young T H, Chang W K, Tang H S, Hsu C T
Abstract excerpt
The human cytochrome P4502E1 gene (P4502E1), coding for an ethanol-inducible nitrosamine-metabolizing P-450, is involved in the metabolism of ethanol and many known carcinogens. Recently, restriction fragment length polymorphisms (RFLPs) within the P4502E1 have been suggested as genetic markers o...
Topics
- Adult
- Age Factors
- Aged
- Alleles
- Base Sequence
- China
- Cytochrome P-450 CYP2E1
- Cytochrome P-450 Enzyme System
- Genetic Markers
- Humans
- Liver Diseases, Alcoholic
- Male
- Middle Aged
- Molecular Sequence Data
- Oxidoreductases, N-Demethylating
- Polymorphism, Genetic
- Prevalence