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Article

Polymorphism at the P450IIE1 locus is not associated with alcoholic liver disease in Caucasian men.

Alcoholism, clinical and experimental research - 1 Feb 1995

Carr L G, Hartleroad J Y, Liang Y, Mendenhall C, Moritz T, Thomasson H

Abstract excerpt

Because alcoholic hepatitis and cirrhosis, well-known complications of alcohol abuse, do not occur in all alcoholics, genetic factors such as differences in alcohol-metabolizing enzymes may play a role in the development of alcoholic liver disease. Cytochrome P450IIE1 catalyzes the oxidation of ethanol, producing acetaldehyde and free radicals capable of reacting with and peroxidizing cell membranes....

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Source

Identifiers

PMID: 7771648
DOI: 10.1111/j.1530-0277.1995.tb01489.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Polymorphism at the P450IIE1 locus is not associated with alcoholic liver disease in Caucasian men.PMID 7771648Read ↗

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