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Article

The v-erbA oncogene selectively inhibits iodide uptake in rat thyroid cells.

Oncogene - 2 May 1996

Trapasso F, Martelli M L, Battaglia C, Angotti E, Mele E, Stella A, Samarut J, Avvedimento V E, Fusco A

Abstract excerpt

v-erbA is the oncogenic form of the c-erbA proto-oncogene, which encodes the receptor for thyroid hormones. The expression of the v-erbA oncogene in thyroid differentiated cells, PC Cl 3, inhibits iodide uptake and thyrotropin-dependent growth, whereas it has no effect on the expression of the other thyroid specific markers, i.e. thyroglobulin, thyroperoxidase and thyrotropin receptor. The activity of...

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PMID: 8649848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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