Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Determination of the allele-specific antigen-binding site on I-Ak and I-Ab molecules.

European journal of immunology - 1 Jun 1996

Itoh Y, Kajino K, Ogasawara K, Katoh M, Namba K, Takami K, Iwabuchi K, Braunstein N S, Onoé K

Abstract excerpt

Residues 46 and 54 on a pigeon cytochrome c 43-58 analog, 50E, function as major histocompatibility complex class II contact sites. A peptide, 46F50E54A, with phenylalanine (F) at position 46 and alanine (A) at 54 on 50E bound to Ab and a peptide, 46D50E54A, with aspartic acid (D) at 46 and alanine at 54, bound to Ak. To determine the allele-specific peptide contact sites on I-A molecules corresponding to the I-A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Binding Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Peptides

Share to Sequence Alignment

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 8647211
DOI: 10.1002/eji.1830260621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Determination of the allele-specific antigen-binding site on I-Ak and I-Ab molecules.PMID 8647211Read ↗

[Analysis of the allele specific Ag-binding site on murine class II MHC].Semantic proximity Read ↗

[Detection of amino acids on the agretopes of pigeon cytochrome c derived peptide p43-58 specifically bound to mouse MHC class II allelic products].Semantic proximity Read ↗

The specificity of alloreactive T cells is determined by MHC polymorphisms which contact the T cell receptor and which influence peptide binding.Semantic proximity Read ↗

Functional and molecular characterization of I-A kappa beta mutants is consistent with the predicted three dimensional structure of class II MHC molecules.Semantic proximity Read ↗

Mutations in human CD4 impair the functional interaction with different human and mouse class II isotypes and alleles.Semantic proximity Read ↗

A strategy for making synthetic peptide vaccines.Semantic proximity Read ↗

Molecular characterization of an arthritogenic collagen peptide interacting with I-Ar.Semantic proximity Read ↗

Polymorphism at beta 85 and not beta 86 of HLA-DR1 is predominantly responsible for restricting the nature of the anchor side chain: implication for concerted effects of class II MHC polymorphism.Semantic proximity Read ↗

Evidence for a functional interaction between the beta chain of major histocompatibility complex class II and the T cell receptor alpha chain during recognition of a bacterial superantigen.Semantic proximity Read ↗

Identification of amino acids in HLA-DPw4b beta and -DR5 beta 1 chains that are involved in antibody binding epitopes using site-directed mutagenesis and DNA-mediated gene transfer.Semantic proximity Read ↗

I-J as an idiotype of the recognition component of antigen-specific suppressor T-cell factor.Semantic proximity Read ↗

Cell surface expression of hybrid murine/human MHC class II beta alpha dimers. Key influence of residues in the amino-terminal portion of the beta 1 domain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.