Article
Determination of the allele-specific antigen-binding site on I-Ak and I-Ab molecules.
European journal of immunology - 1 Jun 1996
Itoh Y, Kajino K, Ogasawara K, Katoh M, Namba K, Takami K, Iwabuchi K, Braunstein N S, Onoé K
Abstract excerpt
Residues 46 and 54 on a pigeon cytochrome c 43-58 analog, 50E, function as major histocompatibility complex class II contact sites. A peptide, 46F50E54A, with phenylalanine (F) at position 46 and alanine (A) at 54 on 50E bound to Ab and a peptide, 46D50E54A, with aspartic acid (D) at 46 and alani...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Binding Sites
- Binding, Competitive
- Histocompatibility Antigens Class II
- Hybridomas
- Mice
- Molecular Sequence Data
- Peptides
- Sequence Alignment
- Sequence Homology, Amino Acid