Article
I-J as an idiotype of the recognition component of antigen-specific suppressor T-cell factor.
Nature - 1 Jan 2000
Sumida T, Sado T, Kojima M, Ono K, Kamisaku H, Taniguchi M
Abstract excerpt
The I-J determinant of membrane glycoprotein is known to be expressed exclusively on suppressor T cells (TS), which have a crucial role in the regulation of immune responses. I-J also comprises part of the soluble factor (TSF) with suppressor activity which is secreted from TS. Gene-mapping experiments have indicated that the I-J gene lies between the I-A and I-E subregions of the mouse major histocompatibility...
Topics
- Animals
- Antigen-Presenting Cells
- Chimera
- Chromosome Mapping
- Epitopes
- H-2 Antigens
- Lymphokines
- Major Histocompatibility Complex
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL