Article
A strategy for making synthetic peptide vaccines.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1992
Ogasawara K, Naruse H, Itoh Y, Gotohda T, Arikawa J, Kida H, Good R A, Onoé K
Abstract excerpt
We have determined the H-2 class II allele-specific amino acid motif of the agretope (the site of contact between the peptide antigen and the major histocompatibility complex) for a synthetic peptide composed of residues 43-58 of pigeon cytochrome c (p43-58). Residues 46 and 54 functioned as the...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibody Formation
- Cell Line
- Dogs
- Enzyme-Linked Immunosorbent Assay
- Genes, MHC Class II
- Influenza A virus
- Influenza Vaccines
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Neutralization Tests
- Peptides
- T-Lymphocytes
- T-Lymphocytes, Helper-Inducer
- Vaccines, Synthetic