Article
A strategy for making synthetic peptide vaccines.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1992
Ogasawara K, Naruse H, Itoh Y, Gotohda T, Arikawa J, Kida H, Good R A, Onoé K
Abstract excerpt
We have determined the H-2 class II allele-specific amino acid motif of the agretope (the site of contact between the peptide antigen and the major histocompatibility complex) for a synthetic peptide composed of residues 43-58 of pigeon cytochrome c (p43-58). Residues 46 and 54 functioned as the agretope, and residues 50 and 52 functioned as the epitope (the site for contact between the peptide antigen and the...
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