Article
Extensive apoptosis in ductal carcinoma in situ of the breast.
Cancer - 1 May 1996
Bodis S, Siziopikou K P, Schnitt S J, Harris J R, Fisher D E
Abstract excerpt
BACKGROUND: More than 50% of breast ductal carcinomas in situ (DCIS) contain significant histologic necrosis, an important prognostic factor for determining recurrence and progression to invasive breast cancer. We have examined whether the mechanism of this spontaneous cell death might be apoptosis, a genetically encoded suicide pathway that may be triggered by various events including dysregulated cell...
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