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Type V collagen regulates the expression of apoptotic and stress response genes by breast cancer cells

5 Aug 2004

Abstract excerpt

Type V collagen is a "minor" component of normal human breast stroma, which is subjected to over-deposition in cases of ductal infiltrating carcinoma (DIC). We reported that, if used as a culture substrate for the DIC cell line 8701-BC, it exhibited poorly-adhesive properties and restrained the proliferative and motile behavior of the cell subpopulation able to attach onto it. Moreover, this collagen species was...

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PMID: 15389593
DOI: 10.1002/jcp.20131

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