Article
Aberrant expression of caspase-14 in epithelial tumors.
Biochemical and biophysical research communications - 23 Sept 2005
Koenig Ulrich, Sommergruber Wolfgang, Lippens Saskia
Abstract excerpt
Cysteine-dependent aspartate-specific proteases (caspases) are the cellular executors of apoptosis. Caspase-14 is the most divergent member of the family of mammalian caspases and displays a variety of unique characteristics. It is expressed in a limited number of tissues and has the shortest amino acid sequence within the caspase protein family. During induction of apoptosis, it is not processed, whereas...
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