Article
Clinicopathologic analysis of bcl-2 immunostaining in breast carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 1996
Visscher D W, Sarkar F, Tabaczka P, Crissman J
Abstract excerpt
Tissue sections of 81 breast carcinomas and 19 benign breast tissues were immunostained with a monoclonal antibody to the bcl-2 gene product, a cytoplasmic protein that regulates apoptosis. The degree of immunoreactivity was then compared with clinicopathologic parameters and to immunostaining for mutated p53 gene product. Immunoreactivity for bcl-2 was present consistently in lymphocyte populations and in...
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