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Article

Premature apoptosis of keratinocytes and the dysregulation of keratinization in porokeratosis

1 Sept 2002

Abstract excerpt

BACKGROUND: Porokeratosis is a dyskeratotic disorder of the skin characterized by cornoid lamella with parakeratosis, hyperkeratosis and loss of granular layers. The pathogenesis of porokeratosis and the mechanism(s) of its abnormal keratinization are still unknown. OBJECTIVE: To elucidate the mechanism(s) of abnormal keratinization that leads to the formation of cornoid lamellae in porokeratosis. METHODS:...

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Identifiers

PMID: 12207590
DOI: 10.1046/j.1365-2133.2002.04853.x

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