Article
Effect of age, ethnicity, and head injury on the association between APOE genotypes and Alzheimer's disease.
Annals of the New York Academy of Sciences - 16 Dec 1996
Tang M X, Maestre G, Tsai W Y, Liu X H, Feng L, Chung W Y, Chun M, Schofield P, Stern Y, Tycko B, Mayeux R
Abstract excerpt
The association between apolipoprotein E (APOE)-epsilon 4 and Alzheimer's disease has been confirmed worldwide. We and others have observed a diminished association in the very old and among African-Americans compared to Caucasians and Hispanics in New York. In this review we describe a new metho...
Topics
- Black or African American
- Age Factors
- Aged
- Alleles
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Craniocerebral Trauma
- Ethnicity
- Female
- Gene Frequency
- Genotype
- Hispanic or Latino
- Humans
- Male