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Article

Effect of age, ethnicity, and head injury on the association between APOE genotypes and Alzheimer's disease.

Annals of the New York Academy of Sciences - 16 Dec 1996

Tang M X, Maestre G, Tsai W Y, Liu X H, Feng L, Chung W Y, Chun M, Schofield P, Stern Y, Tycko B, Mayeux R

Abstract excerpt

The association between apolipoprotein E (APOE)-epsilon 4 and Alzheimer's disease has been confirmed worldwide. We and others have observed a diminished association in the very old and among African-Americans compared to Caucasians and Hispanics in New York. In this review we describe a new method we developed to compare relative risks by APOE genotypes in an expanded cohort of cases and controls from three...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8993479
DOI: 10.1111/j.1749-6632.1996.tb32593.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Effect of age, ethnicity, and head injury on the association between APOE genotypes and Alzheimer's disease.PMID 8993479Read ↗

Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City.Semantic proximity Read ↗

Amyloid beta-protein, APOE genotype and head injury.Semantic proximity Read ↗

Increased risk of dementia following mild head injury for carriers but not for non-carriers of the APOE epsilon4 allele.Semantic proximity Read ↗

Genetics and brain injury: apolipoprotein E.Semantic proximity Read ↗

Head injury and the risk of AD in the MIRAGE study.Semantic proximity Read ↗

Head injury and risk of Alzheimer's disease by apolipoprotein E genotype.Semantic proximity Read ↗

Apolipoprotein E and functional recovery from brain injury following postacute rehabilitation.Semantic proximity Read ↗

The association between APOE epsilon4, age and outcome after head injury: a prospective cohort study.Semantic proximity Read ↗

Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.Semantic proximity Read ↗

Risk of dementia associated with the ApoE epsilon4 allele and falls causing head injury without explicit traumatic brain injury.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury.Semantic proximity Read ↗

Interaction between Apolipoprotein epsilon 4 and traumatic brain injury in patients with Alzheimer's disease and Mild Cognitive Impairment.Semantic proximity Read ↗

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