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Article

APOE region molecular signatures of Alzheimer's disease across races/ethnicities.

Neurobiology of aging - 1 Mar 2020

Kulminski Alexander M, Shu Leonardo, Loika Yury, Nazarian Alireza, Arbeev Konstantin, Ukraintseva Svetlana, Yashin Anatoliy, Culminskaya Irina

Abstract excerpt

The role of even the strongest genetic risk factor for Alzheimer's disease (AD), the apolipoprotein E (APOE) ε4 allele, in its etiology remains poorly understood. We examined molecular signatures of AD defined as differences in linkage disequilibrium patterns between AD-affected and -unaffected whites (2673/16,246), Hispanics (392/867), and African Americans (285/1789), separately. We focused on 29 polymorphisms...

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Source

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Identifiers

PMID: 31813627
DOI: 10.1016/j.neurobiolaging.2019.11.007
PMCID: PMC7064423

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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